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Human Fibroblast Cells
Human fibroblast cells are a type of cell found in the connective tissue of the human body. They play a critical role in maintaining the structural integrity of tissues by producing and secreting extracellular matrix (ECM) components, such as collagen, elastin, and proteoglycans. Fibroblast cells also contribute to wound healing, tissue repair, and remodeling processes.…
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Signaling Molecules
Signaling molecules, also known as signaling ligands or signal molecules, are chemical compounds that transmit information within and between cells to coordinate various cellular processes. These molecules can be small molecules, peptides, or proteins that bind to specific receptors on the surface or within target cells, initiating a series of intracellular events that eventually lead…
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Antibodies
Antibodies, also known as immunoglobulins, are proteins produced by the immune system in response to foreign substances, such as viruses, bacteria, or other antigens. These proteins play a crucial role in the immune response, helping the body to recognize and neutralize foreign invaders. Antibodies are Y-shaped molecules composed of four polypeptide chains: two identical heavy…
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Recombinant Proteins
Recombinant proteins are proteins that are produced by genetically engineered cells, which have been modified to contain a foreign gene encoding the protein of interest. These proteins are often used for research, diagnostic, and therapeutic purposes. The production of recombinant proteins involves introducing a gene encoding the desired protein into a suitable host organism, such…
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Mammalian Production Cell
Mammalian production cells are cell lines derived from mammalian organisms, such as humans, mice, or hamsters, that are widely used in biopharmaceutical manufacturing and scientific research. These cells are employed to produce recombinant proteins, monoclonal antibodies, and other biopharmaceuticals, as well as to study gene expression, protein function, and other cellular processes. Mammalian production cells…
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Simian Virus 40
Simian Virus 40 (SV40) is a polyomavirus that was first discovered in the 1960s in rhesus monkey kidney cells. It is a small, double-stranded DNA virus with a circular genome of approximately 5,200 base pairs. Although SV40 naturally infects monkeys and can cause tumors in them, it does not typically cause disease in humans. However,…
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CV-1
CV-1 (Cercopithecus aethiops-1) is a cell line derived from the kidney of an African green monkey (Cercopithecus aethiops), which is often used in scientific research. It was established in the 1960s and has since been employed in various studies, including virology, molecular biology, and cancer research. CV-1 cells are particularly useful for the study of…
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Fibroblast Cell Line
A fibroblast cell line is a group of fibroblast cells that have been cultured in vitro and can be maintained and propagated for extended periods. Fibroblasts are a type of cell found in the connective tissue of animals and play a crucial role in the synthesis of the extracellular matrix and collagen production, which provide…
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African Green Monkey
African green monkeys (Chlorocebus spp.) are a genus of Old World monkeys native to the forests and savannahs of sub-Saharan Africa. They are also known as vervet monkeys, particularly in the context of the Chlorocebus pygerythrus species. These monkeys are small to medium-sized primates, with a typical body length of 40-60 cm (16-24 inches) and…
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T-antigen
T-antigen, also known as Tumor antigen, refers to a type of protein produced by a virus or a mutated cell that can induce an immune response in the host organism. T-antigens can be found on the surface of cancer cells or in viral-infected cells and are often used by the immune system to identify and…